Choline dihydrogen phosphate, CAS: 83846-92-8

Key Applications:

1. Biocompatible Ionic Liquid for Green Chemistry

• Used as a low‑toxicity, biodegradable ionic liquid in sustainable reaction media.
• Supports enzyme‑catalyzed transformations, including esterification, transesterification, and selective oxidations, due to its compatibility with biological systems.
• Enables milder processing conditions and reduced reliance on volatile organic solvents.

2. Solvent & Co‑solvent in Catalysis

• Functions as a polar protic ionic liquid with strong hydrogen‑bonding capability, improving solubility of polar substrates and intermediates.
• Applied in acid‑catalyzed reactions, including dehydration, esterification, and biomass conversion.
• Enhances catalyst dispersion and stability in heterogeneous and homogeneous catalytic systems.

 3. Biomass Processing & Lignocellulosic Fractionation

• Effective in cellulose swelling, dissolution, and pretreatment, improving enzymatic hydrolysis efficiency.
• Used in hemicellulose extraction and lignin modification workflows.
• Supports integrated biorefinery processes aiming for green solvent cycles and reduced waste.

4. Electrolyte Component in Aqueous and Protic Systems

• Serves as a conductive additive in aqueous electrolyte formulations.
• Investigated for proton‑conducting membranes, fuel cell electrolytes, and solid polymer electrolytes.
• Offers thermal stability and low volatility, improving operational safety.

 5. Stabilizer for Biomolecules & Enzymes

• Used as a protein‑stabilizing ionic liquid, reducing denaturation in storage and processing.
• Supports enzyme immobilization and biocatalytic reactor design.
• Applied in DNA/RNA handling, where choline‑based salts minimize degradation and maintain structural integrity.

6. Additive in Formulations & Surfactant Systems

• Acts as a hydrogen‑bonding, pH‑modulating component in surfactant blends.
• Used in personal‑care formulations, detergents, and agrochemical carriers where biocompatibility is essential.
• Improves solubilization of polar actives and enhances formulation stability.

 7. Corrosion Inhibition & Metal Surface Treatment

• Forms protective phosphate‑based layers on metal surfaces.
• Applied in aqueous corrosion‑inhibitor packages, especially for steel and aluminum.
• Useful in metal cleaning, passivation, and anti‑rust coatings.

8. Polymer Processing & Material Modification

• Functions as a plasticizer or ionic additive in biopolymers such as cellulose acetate, PLA, and chitosan.
• Enhances ionic conductivity, flexibility, and thermal stability in polymer electrolytes.
• Supports ion‑exchange membrane fabrication and proton‑conducting polymer development.

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