1-(4-sulfobutyl)-3-methylimidazolium triflate, CAS: 657414-80-7

Key Application:

Synthesis

• Functions as a polar, non-volatile reaction medium for nucleophilic substitutions, esterifications, and acid-promoted transformations.
• Enhances solubility of multifunctional or ionic substrates, supporting higher reaction homogeneity and improved yields.
• Serves as a recyclable solvent phase for multi-step synthetic sequences requiring controlled acidity.

Catalysis

• Acts as a Brønsted acidic ionic liquid catalyst for dehydration, alkylation, and rearrangement reactions.
• Stabilizes carbocationic and polar transition states, enabling milder reaction conditions and reduced byproduct formation.
• Supports biphasic catalytic systems where the ionic liquid phase retains the catalyst for reuse.

Extraction

• Effective in liquid–liquid extraction of metal ions, polar organics, and biomass-derived intermediates due to its strong hydrophilicity and tunable acidity.
• Facilitates selective extraction of charged or highly polar species that exhibit limited solubility in conventional organic solvents.
• Useful in preconcentration workflows for analytical chemistry and environmental monitoring.

Separation

• Employed as a stationary-phase additive or mobile-phase modifier in chromatography to improve resolution of polar analytes.
• Enhances phase behavior in aqueous biphasic systems, enabling selective partitioning of biomolecules, metal salts, and fine chemicals.
• Supports membrane-based separations by improving ion transport and modulating solvent polarity.

Please contact us if you want to learn more or need assistance with your order.